Annals of Epidemiology
Volume 17, Issue 9 , Pages 689-696, September 2007

Regional Differences in African Americans' High Risk for Stroke: The Remarkable Burden of Stroke for Southern African Americans

From the University of Alabama School of Public Health, Departments of Biostatistics (G.H., J.H.) and Epidemiology (V.J.H.), Birmingham; and the Division for Heart Disease and Stroke Prevention, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, Atlanta, GA (D.R.L., S.Y.)

Received 14 November 2006; accepted 29 March 2007.

Purpose

The stroke mortality rate for African Americans aged 45 to 64 years is 3 to 4 times higher than for whites of the same age, with a decreasing black-to-white mortality ratio with increasing age. There is also a “STROKE BELT” with higher stroke mortality in the southeastern United States. This study assesses if there are also geographic variations in the magnitude of the excess stroke mortality for African Americans.

Methods

The age- and sex-specific black-to-white mortality ratio was calculated for each of 26 states with a sufficient African American population for stable estimates. The southern excess was calculated as the percentage excess of southern over nonsouthern rates.

Results

Across age and sex strata, the black-to-white stroke mortality ratio was consistently higher for southern states, with an average black-to-white stroke mortality ratio that ranged from 6% to 21% higher among southern states than in nonsouthern states.

Conclusions

The increase in stroke mortality rates for African Americans in southern states is even larger than expected. That southern states that are not part of the “STROKE BELT” (Virginia and Florida) also have an elevated black-to-white mortality ratio suggests the mechanism of higher risk for African Americans may be independent of the causes contributing to “STROKE BELT.”

Key Words: Cerebrovascular Accident, Mortality, Continental Population Groups, African Americans, Geography

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PII: S1047-2797(07)00153-6

doi:10.1016/j.annepidem.2007.03.019

Annals of Epidemiology
Volume 17, Issue 9 , Pages 689-696, September 2007