Annals of Epidemiology
Volume 11, Issue 7 , Pages 477-483 , October 2001

Hospitalization with Respiratory Disease Following Hiatal Hernia and Reflux Esophagitis in a Prospective, Population-Based Study

  • Constance E Ruhl, MD, PhD

      Affiliations

    • From Social and Scientific Systems, Inc., Bethesda, MD USA
    • Corresponding Author InformationAddress correspondences to: Dr. C. E. Ruhl, Social and Scientific Systems, Inc., Suite 1300, 7101 Wisconsin Ave., Bethesda, MD 20814-4805
    • ,
  • Amnon Sonnenberg, MD

      Affiliations

    • Department of Veterans Affairs and University of New Mexico, Albuquerque, NM USA
    • ,
  • James E Everhart, MD, MPH

      Affiliations

    • National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD USA

Received 6 September 2000 ,Revised 28 February 2001 ,Accepted 26 March 2001.

References 

  1. Mays EE. Intrinsic asthma in adults. Association with gastroesophageal reflux. JAMA. 1976;236:2626–2628
  2. Goodall RJ, Earis JE, Cooper DN, Bernstein A, Temple JG. Relationship between asthma and gastro-oesophageal reflux. Thorax. 1981;36:116–121
  3. Sontag S, O'Connell S, Greenlee H, Schnell T, Chintam R, Nemchausky B, et al.  Is gastroesophageal reflux a factor in some asthmatics?. Am J Gastroenterol. 1987;82:119–126
  4. Sontag SJ, O'Connell S, Khandelwal S, Miller T, Nemchausky B, Schnell TG, et al.  Most asthmatics have gastroesophageal reflux with or without bronchodilator therapy. Gastroenterology. 1990;99:613–620
  5. Larrain A, Carrasco E, Galleguillos F, Sepulveda R, Pope CE. Medical and surgical treatment of nonallergic asthma associated with gastroesophageal reflux. Chest. 1991;99:1330–1335
  6. Sontag SJ, Schnell TG, Miller TQ, Khandelwal S, O'Connell S, Chejfec G, et al.  Prevalence of oesophagitis in asthmatics. Gut. 1992;33:872–876
  7. Meier JH, McNally PR, Punja M, Freeman SR, Sudduth RH, Stocker N, et al.  Does omeprazole (Prilosec) improve respiratory function in asthmatics with gastroesophageal reflux? A double-blind, placebo-controlled crossover study. Dig Dis Sci. 1994;39:2127–2133
  8. Delahunty JE. Acid laryngitis. J Laryngol Otol. 1972;86:335–342
  9. Ward PH, Berci G. Observations on the pathogenesis of chronic non-specific pharyngitis and laryngitis. Laryngoscope. 1982;92:1377–1382
  10. Kambic V, Radsel Z. Acid posterior laryngitis. Aetiology, histology, diagnosis and treatment. J Laryngol Otol. 1984;98:1237–1240
  11. Jacob P, Kahrilas PJ, Herzon G. Proximal esophageal pH-metry in patients with reflux laryngitis. Gastroenterology. 1991;100:305–310
  12. Deveney CW, Benner K, Cohen J. Gastroesophageal reflux and laryngial disease. Arch Surg. 1993;128:1021–1025
  13. Kamel PL, Hanson D, Kahrilas PJ. Omeprazole for the treatment of posterior laryngitis. Am J Med. 1994;96:321–326
  14. Shaker R, Milbrath M, Ren J, Toohill R, Hogan WJ, Li Q, et al.  Esophagopharyngeal distribution of refluxed gastric acid in patients with reflux laryngitis. Gastroenterology. 1995;109:1575–1582
  15. Hanson DG, Kamel PL, Kahrilas PJ. Outcomes of antireflux therapy for the treatment of chronic laryngitis. Ann Otol Rhinol Laryngol. 1995;104:550–555
  16. Cherry J, Margulies SI. Contact ulcer of the larynx. Laryngoscope. 1968;78:1937–1940
  17. Goldberg M, Noyek AM, Pritzker KP. Laryngeal granuloma secondary to gastro-esophageal reflux. J Otolaryngol. 1978;7:196–202
  18. Ohman L, Olofsson J, Tibbling L, Ericsson G. Esophageal dysfunction in patients with contact ulcer of the larynx. Ann Otol Rhinol Laryngol. 1983;92:228–230
  19. Bogdasarian RS, Olson NR. Posterior glottic laryngeal stenosis. Otolaryngol Head Neck Surg. 1980;88:765–772
  20. Bain WM, Harrington JW, Thomas LE, Schaefer SD. Head and neck manifestations of gastroesophageal reflux. Laryngoscope. 1983;93:175–179
  21. Little FB, Koufman JA, Kohut RI, Marshall RB. Effect of gastric acid on the pathogenesis of subglottic stenosis. Ann Otol Rhinol Laryngol. 1985;94:516–519
  22. Kennedy JH. Silent gastroesophageal reflux (An important but little known cause of pulmonary complications). Dis Chest. 1962;42:42–45
  23. Mays EE, Dubois JJ, Hamilton GB. Pulmonary fibrosis associated with tracheobronchial aspiration. A study of the frequency of hiatal hernia and gastroesophageal reflux in interstitial pulmonary fibrosis of obscure etiology. Chest. 1976;69:512–515
  24. Irwin RS, Zawacki JK, Curley FJ, French CL, Hoffman PJ. Chronic cough as the sole presenting manifestation of gastroesophageal reflux. Am Rev Respir Dis. 1989;140:1294–1300
  25. Ing AJ, Ngu MC, Breslin AB. Chronic persistent cough and gastro-oesophageal reflux. Thorax. 1991;46:479–483
  26. McNally PR, Maydonovitch CL, Prosek RA, Collette RP, Wong RK. Evaluation of gastroesophageal reflux as a cause of idiopathic hoarseness. Dig Dis Sci. 1989;34:1900–1904
  27. Wiener GJ, Koufman JA, Wu WC, Cooper JB, Richter JE, Castell DO. Chronic hoarseness secondary to gastroesophageal reflux disease (documentation with 24-h ambulatory pH monitoring). Am J Gastroenterol. 1989;84:1503–1508
  28. Morrison MD. Is chronic gastroesophageal reflux a causative factor in glottic carcinoma?. Otolaryngol Head Neck Surg. 1988;99:370–373
  29. Ward PH, Hanson DG. Reflux as an etiological factor of carcinoma of the laryngopharynx. Laryngoscope. 1988;98:1195–1199
  30. Ruth M, Mansson I, Sandberg N. The prevalence of symptoms suggestive of esophageal disorders. Scand J Gastroenterol. 1991;26:73–81
  31. Raiha IJ, Impivaara O, Seppala M, Sourander LB. Prevalence and characteristics of symptomatic gastroesophageal reflux disease in the elderly. J Am Geriatr Soc. 1992;40:1209–1211
  32. Kennedy TM, Jones RH, Hungin AP, O'Flanagan H, Kelly P. Irritable bowel syndrome, gastro-oesophageal reflux, and bronchial hyper-responsiveness in the general population. Gut. 1998;43:770–774
  33. Andersen LI, Jensen G. Prevalence of benign oesophageal disease in the Danish population with special reference to pulmonary disease. J Intern Med. 1989;225:393–402
  34. el-Serag HB, Sonnenberg A. Comorbid occurrence of laryngeal or pulmonary disease with esophagitis in United States military veterans. Gastroenterology. 1997;113:755–760
  35. McKinney WP, McIntire DD, Carmody TJ, Joseph A. Comparing the smoking behavior of veterans and nonveterans. Public Health Rep. 1997;112:212–217
  36. Locke GR, Talley NJ, Fett SL, Zinsmeister AR, Melton LJ. Prevalence and clinical spectrum of gastroesophageal reflux (a population-based study in Olmsted County, Minnesota). Gastroenterology. 1997;112:1448–1456
  37. Miller HW: Plan and operation of the health and nutrition examination survey, United States 1971–1793, part A-development, plan, and operation. In Vital and Health Statistics, Series 1, No. 10a. DHEW publication No. (PHS) 76-1310. Hyattsville, Maryland, National Center for Health Statistics, 1973, pp 1–46.
  38. Engel A, Murphy RS, Maurer K, Collins E.: Plan and operation of the NHANES I Augmentation Survey of adults 25–74 years, United States 1974–1975. In Vital and Health Statistics, Series 1, No. 14. DHEW publication No. (PHS) 78-1314. Hyattsville, Maryland, National Center for Health Statistics, 1978, pp 1–10.
  39. Cohen BB, Barbano HE, Cox CS, Feldman JJ, Finucane FF, Kleinman JC, et al.: Plan and operation of the NHANES I Epidemiologic Followup Study, 1982–84. In Vital and Health Statistics, Series 1, No. 22. DHEW publication No. (PHS) 87-1324. Hyattsville, Maryland, National Center for Health Statistics, 1987, pp 1–20.
  40. Finucane FF, Freid VM, Madans JH, et al.: Plan and operation of the NHANES I Epidemiologic Followup Study, 1986. In Vital and Health Statistics, Series 1, No. 25. DHEW publication No. (PHS) 90-1307. Hyattsville, Maryland, National Center for Health Statistics, 1990, pp 1–25.
  41. Cox CS, Rothwell ST, Madans JH, et al.: Plan and operation of the NHANES I Epidemiologic Followup Study, 1987. In Vital and Health Statistics, Series 1, No. 27. DHEW publication No. (PHS) 92-1303. Hyattsville, Maryland, National Center for Health Statistics, 1992, pp 1–26.
  42. International Classification of Diseases, 9th Revision, Clinical Modification, 4th Edition, Vol 1. DHEW publication No. (PHS) 91-1260. U.S. Department of Health and Human Services, 1991.
  43. Ruhl CE, Everhart JE. Overweight, but not high dietary fat intake, increases risk of gastroesophageal reflux disease hospitalization (The NHANES I Epidemiologic Followup Study). Ann Epidemiol. 1999;9:424–435
  44. SAS Institute, Inc . SAS/STAT software (changes and enhancements through release 6.12). Cary (NC): SAS Institute, Inc; 1997;
  45. Kleinbaum DG. Survival analysis (a self-learning text). New York: Springer; 1996;
  46. Stein MR. Gastroesophageal reflux disease and airway disease. New York: Marcel Dekker, Inc; 1999;
  47. Crausaz FM, Favez G. Aspiration of solid food particles into lungs of patients with gastroesophageal reflux and chronic bronchial disease. Chest. 1988;93:376–378
  48. Mansfield LE, Stein MR. Gastroesophageal reflux and asthma (a possible reflex mechanism). Ann Allergy. 1978;41:224–226
  49. Kjellen G, Tibbling L, Wranne B. Bronchial obstruction after oesophageal acid perfusion in asthmatics. Clin Physiol. 1981;1:285–292
  50. Ing AJ, Ngu MC, Breslin AB. Pathogenesis of chronic persistent cough associated with gastroesophageal reflux. Am J Respir Crit Care Med. 1994;149:160–167
  51. Ott DJ, Wu WC, Gelfand DW. Reflux esophagitis revisited (prospective analysis of radiologic accuracy). Gastrointest Radiol. 1981;6:1–7
  52. el-Serag HB, Sonnenberg A. Opposing time trends of peptic ulcer and reflux disease. Gut. 1998;43:327–333

☆ The work was supported through a contract from the National Institute of Diabetes and Digestive and Kidney Diseases (#NO1-DK-6-2220)

PII: S1047-2797(01)00236-8

Annals of Epidemiology
Volume 11, Issue 7 , Pages 477-483 , October 2001

Article Tools

* Image Usage & Resolution