Annals of Epidemiology
Volume 16, Issue 2 , Pages 78-84 , February 2006

Social Integration and Concentrations of C-Reactive Protein Among US Adults

  • Earl S. Ford, MD, MPH

      Affiliations

    • Corresponding Author InformationAddress correspondence to: Earl S. Ford, M.D., M.P.H., Centers for Disease Control and Prevention, 4770 Buford Highway, MS K66, Atlanta, GA 30341. Tel.: (770) 488-2484; fax: (770) 488-8150.
    • ,
  • Eric B. Loucks, PhD
    • ,
  • Lisa F. Berkman, PhD

Received 22 April 2005 ,Accepted 9 August 2005.

References 

  1. Berkman LF, Syme SL. Social networks, host resistance, and mortality: A nine-year follow-up study of Alameda County residents. Am J Epidemiol. 1979;109:186–204
  2. House JS, Landis KR, Umberson D. Social relationships and health. Science. 1988;241:540–545
  3. Seeman TE, Kaplan GA, Knudsen L, Cohen R, Guralnik J. Social network ties and mortality among the elderly in the Alameda County study. Am J Epidemiol. 1987;126:714–723
  4. Orth-Gomer K, Rosengren A, Wilhelmsen L. Lack of social support and incidence of coronary heart disease in middle-aged Swedish men. Psychosom Med. 1993;55:37–43
  5. Eng PM, Rimm EB, Fitzmaurice G, Kawachi I. Social ties and change in social ties in relation to subsequent total and cause-specific mortality and coronary heart disease incidence in men. Am J Epidemiol. 2002;155:700–709
  6. Berkman LF, Vaccarino V, Seeman TE. Gender differences in cardiovascular morbidity and mortality: The contribution of social networks and support. Ann Behav Med. 1993;15:112–118
  7. Shumaker SA, Hill DR. Gender differences in social support and physical health. Health Psychol. 1991;10:102–111
  8. Rothman KJ, Greenland S. Causation and causal inference. In:  Rothman KJ,  Greenland S editor. Modern Epidemiology. Philadelphia: Lippincott Williams & Williams; 1998;p. 7–28
  9. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office of Smoking and Health. Introduction and approach to causal inference. In The Health Consequences of Smoking: A Report of the Surgeon General. Atlanta, GA; Centers for Disease Control and Prevention; 2004:1–33.
  10. Pearson TA, Mensah GA, Alexander RW, Anderson JL, Cannon RO, Criqui M, et al. Markers of inflammation and cardiovascular disease: Application to clinical and public health practice: A statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association. Circulation. 2003;107:499–511
  11. Danesh J, Wheeler J, Hirschfield G, Eda S, Eiriksdottir G, Rumley A, et al. C-Reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease. N Engl J Med. 2004;350:1387–1397
  12. Centers for Disease Control and Prevention. Plan and operation of the Third National Health and Nutrition Examination Survey, 1988-94. Bethesda, MD: National Center for Health Statistics. Vital Health Stat. 1994;1:1–407.
  13. Centers for Disease Control and Prevention. The Third National Health and Nutrition Examination Survey (NHANES III 1988-94) Reference Manuals and Reports. Bethesda, MD: National Center for Health Statistics (CD-ROM); 1996;
  14. Berkman LF, Melchior M, Chastang JF, Niedhammer I, Leclerc A, Goldberg M. Social integration and mortality: A prospective study of French employees of Electricity of France-Gas of France: The GAZEL cohort. Am J Epidemiol. 2004;159:167–174
  15. Seeman TE, Berkman LF, Kohout F, LaCroix A, Glynn R, Blazer D. Intercommunity variations in the association between social ties and mortality in the elderly: A comparative analysis of three communities. Ann Epidemiol. 1993;3:325–335
  16. Gunter EW, Lewis BL, Koncikowski SM. Laboratory methods used for the Third National Health and Nutrition Examination Survey (NHANES III), 1988-1994. Included in CD-ROM 6-0178, NHANES III Reference Manuals and Reports. Hyattsville, MD: Centers for Disease Control and Prevention; 1996;
  17. Rosengren A, Wilhelmsen L, Welin L, Tsipogianni A, Teger-Nilsson AC, Wedel H. Social influences and cardiovascular risk factors as determinants of plasma fibrinogen concentration in a general population sample of middle aged men. BMJ. 1990;300:634–638
  18. Helminen A, Rankinen T, Vaisanen S, Rauramaa R. Social network in relation to plasma fibrinogen. J Biosoc Sci. 1997;29:129–139
  19. Davis MC, Swan PD. Association of negative and positive social ties with fibrinogen levels in young women. Health Psychol. 1999;18:131–139
  20. Wamala SP, Murray MA, Horsten M, Eriksson M, Schenck-Gustafsson K, Hamsten A, et al. Socioeconomic status and determinants of hemostatic function in healthy women. Arterioscler Thromb Vasc Biol. 1999;19:485–492
  21. Steptoe A, Kunz-Ebrecht S, Owen N, Feldman PJ, Rumley A, Lowe GD, et al. Influence of socioeconomic status and job control on plasma fibrinogen responses to acute mental stress. Psychosom Med. 2003;65:137–144
  22. Loucks EB, Berkman LF, Gruenewald TF, Seeman TE. Social integration is associated with fibrinogen concentration in elderly men. Psychosom Med. 2005;67:353–358
  23. Hirschfield GM, Pepys MB. C-Reactive protein and cardiovascular disease: New insights from an old molecule. QJM. 2003;96:793–807
  24. Maes M, Song C, Lin A, De Jongh R, Van Gastel A, Kenis G, et al. The effects of psychological stress on humans: Increased production of pro-inflammatory cytokines and a Th1-like response in stress-induced anxiety. Cytokine. 1998;10:313–318
  25. Steptoe A, Willemsen G, Owen N, Flower L, Mohamed-Ali V. Acute mental stress elicits delayed increases in circulating inflammatory cytokine levels. Clin Sci (Lond). 2001;101:185–192
  26. Lutgendorf SK, Garand L, Buckwalter KC, Reimer TT, Hong SY, Lubaroff DM. Life stress, mood disturbance, and elevated interleukin-6 in healthy older women. J Gerontol A Biol Sci Med Sci. 1999;54:M434–M439
  27. Brydon L, Edwards S, Mohamed-Ali V, Steptoe A. Socioeconomic status and stress-induced increases in interleukin-6. Brain Behav Immun. 2004;18:281–290
  28. Miller RJ, Sutherland AG, Hutchison JD, Alexander DA. C-Reactive protein and interleukin 6 receptor in post-traumatic stress disorder: A pilot study. Cytokine. 2001;13:253–255
  29. Danner M, Kasl SV, Abramson JL, Vaccarino V. Association between depression and elevated C-reactive protein. Psychosom Med. 2003;65:347–356
  30. Penninx BW, Kritchevsky SB, Yaffe K, Newman AB, Simonsick EM, Rubin S, et al. Inflammatory markers and depressed mood in older persons: Results from the Health, Aging and Body Composition study. Biol Psychiatry. 2003;54:566–572
  31. Tiemeier H, Hofman A, van Tuijl HR, Kiliaan AJ, Meijer J, Breteler MM. Inflammatory proteins and depression in the elderly. Epidemiology. 2003;14:103–107
  32. Seeman TE, McEwen BS. Impact of social environment characteristics on neuroendocrine regulation. Psychosom Med. 1996;58:459–471
  33. Uchino BN, Cacciopo JT, Kiecolt-Glaser JK. The relationship between social support and physiological processes: A review with emphasis on underlying mechanisms and implications for health. Psychol Bull. 1996;119:488–531
  34. Ford ES, Giles WH, Mokdad AH, Myers GL. Distribution and correlates of C-reactive protein concentrations among adult US women. Clin Chem. 2004;50:574–581
  35. Koenig W, Sund M, Frohlich M, Fischer HG, Lowel H, Doring A, et al. C-Reactive protein, a sensitive marker of inflammation, predicts future risk of coronary heart disease in initially healthy middle-aged men: Results from the MONICA (Monitoring Trends and Determinants in Cardiovascular Disease) Augsburg Cohort Study, 1984 to 1992. Circulation. 1999;99:237–242
  36. Hemingway H, Marmot M. Evidence based cardiology: Psychosocial factors in the aetiology and prognosis of coronary heart disease. Systematic review of prospective cohort studies. BMJ. 1999;318:1460–1467

PII: S1047-2797(05)00316-9

doi: 10.1016/j.annepidem.2005.08.005

Annals of Epidemiology
Volume 16, Issue 2 , Pages 78-84 , February 2006

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