I. Moderate Drinking and Cardiovascular DiseaseAlcohol and Coronary Heart Disease: Drinking Patterns and Mediators of Effect
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Cited by (62)
Moderate alcohol consumption and lower total mortality risk: Justified doubts or established facts?
2019, Nutrition, Metabolism and Cardiovascular DiseasesCitation Excerpt :The lower mortality risk among moderate drinkers is thought to be mainly explained by its effects on several cardio-protective pathways. Numerous experimental studies have shown beneficial changes in high-density lipoprotein cholesterol, clotting factors, endothelial function, insulin sensitivity, and inflammation [47,48]. All these findings support biological plausibility of beneficial effects of moderate alcohol consumption as shown in observational studies.
Longitudinal study of alcohol consumption and HDL concentrations: A community-based study
2017, American Journal of Clinical NutritionLight-to-moderate drinking and incident heart failure - The Norwegian HUNT study
2016, International Journal of CardiologyCitation Excerpt :Our results suggest that a pattern similar to that observed for IHD may be present also in case of HF, namely that greater drinking frequency with limited quantity consumed per drinking day may be most favorable among light-to-moderate drinkers [7,33]. Furthermore, findings from earlier studies on IHD have consistently suggested that binge drinking (i.e., heavy episodic drinking in a short period of time [34]) has a detrimental health effect [33,35]. We could not explicitly examine binge drinking in this study, but found that the apparently lower risk of HF among moderate drinkers was completely absent among those who indicated drinking problems on the CAGE questionnaire.
Joint associations of alcohol consumption and physical activity with all-cause and cardiovascular mortality
2013, American Journal of CardiologyCitation Excerpt :Furthermore, binge and/or heavy drinking is linked with adverse cardiovascular disease risk factors such as elevated blood pressure, adverse changes in fibrinolytic factors, cardiac arrhythmia, cardiomyopathy, and heightened platelet activation.22,23 Assuming causal associations, a possible explanation for our results is that the effects of physical activity might enhance the positive effects of moderate alcohol consumption on high-density lipoprotein levels in moderate drinkers.21,22 Furthermore, heavy or binge drinking might increase carcinogenic processes, as physical activity might inhibit these processes, although this is not yet established.24