Annals of Epidemiology
Volume 19, Issue 7 , Pages 441-445 , July 2009

Vitamin D and Cancer Mini-Symposium: The Risk of Additional Vitamin D

  • Reinhold Vieth

      Affiliations

    • Corresponding Author InformationAddress correspondence to: Reinhold Vieth, PhD, FCACB, Pathology and Laboratory Medicine, Mount Sinai Hospital, 600 University Ave., Toronto, ON, M5G 1X5, Canada. Tel.: (416) 586-5920; fax: (416) 586-8628.

Received 25 April 2007 ,Accepted 16 January 2009.

References 

  1. Standing Committee on the Scientific Evaluation of Dietary Reference Intakes. Dietary reference intakes: calcium, phosphorus, magnesium, vitamin D, and fluoride. Washington, DC: National Academy Press; 1997;
  2. Gilchrest BA. Sun protection and Vitamin D: three dimensions of obfuscation. J Steroid Biochem Mol Biol. 2007;103:655–663
  3. Lim HW, Gilchrest BA, Cooper KD, Bischoff-Ferrari HA, Rigel DS, Cyr WH, et al. Sunlight, tanning booths, and vitamin D. J Am Acad Dermatol. 2005;52:868–876
  4. Murphy MJ. Rodenticides. Vet Clin North Am Small Anim Pract. 2002;32:469–484viii
  5. Shephard RM, DeLuca HF. Plasma concentrations of vitamin D3 and its metabolites in the rat as influenced by vitamin D3 or 25-hydroxyvitamin D3 intakes. Arch Biochem Biophys. 1980;202:43–53
  6. Thorin E, Henrion D, Oster L, Thorin-Trescases N, Capdeville C, Martin JA, et al. Vascular calcium overload produced by administration of vitamin D3 and nicotine in rats. Changes in tissue calcium levels, blood pressure, and pressor responses to electrical stimulation or norepinephrine in vivo. J Cardiovasc Pharmacol. 1990;16:257–266
  7. Stein RB. Ionic currents in nerve and muscle. In: Nerve and muscle. New York: Plenum Press; 1980;p. 45–63
  8. Robinson BG, Clifton-Bligh P, Posen S, Morris BJ. Plasma vasopressin in hypercalcaemic states. Aust N Z J Med. 1983;13:5–7
  9. Vieth R, Pinto T, Reen BS, Wong MM. Vitamin D poisoning by table sugar. Lancet. 2002;359:672
  10. Vieth R. Vitamin D supplementation, 25-hydroxyvitamin D concentrations, and safety. Am J Clin Nutr. 1999;69:842–856
  11. Eaton SB. The ancestral human diet: what was it and should it be a paradigm for contemporary nutrition?. Proc Nutr Soc. 2006;65:1–6
  12. Webb AR, DeCosta BR, Holick MF. Sunlight regulates the cutaneous production of vitamin D3 by causing its photodegradation. J Clin Endocrinol Metab. 1989;68:882–887
  13. Dent CE, Round JM, Rowe DJ, Stamp TC. Effect of chapattis and ultraviolet irradiation on nutritional rickets in an Indian immigrant. Lancet. 1973;1:1282–1284
  14. Falkenbach A, Unkelbach U, Boehm BO, Regeniter A, Stein J, Seiffert U, et al. Bone metabolism before and after irradiation with ultraviolet light. Eur J Appl Physiol. 1993;66:55–59
  15. Krause R, Buhring M, Hopfenmuller W, Holick MF, Sharma AM. Ultraviolet B and blood pressure [letter]. Lancet. 1998;352:709–710
  16. Matsuoka LY, Wortsman J, Hollis BW. Suntanning and cutaneous synthesis of vitamin D3. J Lab Clin Med. 1990;116:87–90
  17. Mawer EB, Berry JL, Sommer-Tsilenis E, Beykirch W, Kuhlwein A, Rohde BT. Ultraviolet irradiation increases serum 1,25-dihydroxyvitamin D in vitamin-D-replete adults. Miner Electrolyte Metab. 1984;10:117–121
  18. Stamp TC, Haddad JG, Twigg CA. Comparison of oral 25-hydroxycholecalciferol, vitamin D, and ultraviolet light as determinants of circulating 25-hydroxyvitamin D. Lancet. 1977;1:1341–1343
  19. arghese M, Rodman JS, Williams JJ, Brown A, Carter DM, Zerwekh JE, et al. The effect of ultraviolet B radiation treatments on calcium excretion and vitamin D metabolites in kidney stone formers. Clin Nephrol. 1989;31:225–231
  20. Barger-Lux MJ, Heaney RP, Dowell S, Chen TC, Holick MF. Vitamin D and its major metabolites: serum levels after graded oral dosing in healthy men. Osteoporos Int. 1998;8:222–230
  21. Blank S, Scanlon KS, Sinks TH, Lett S, Falk H. An outbreak of hypervitaminosis D associated with the overfortification of milk from a home-delivery dairy. Am J Public Health. 1995;85:656–659
  22. Koutkia P, Chen TC, Holick MF. Vitamin D intoxication associated with an over-the-counter supplement. N Engl J Med. 2001;345:66–67
  23. Pettifor JM, Bikle DD, Cavaleros M, Zachen D, Kamdar MC, Ross FP. Serum levels of free 1,25-dihydroxyvitamin D in vitamin D toxicity. Ann Intern Med. 1995;122:511–513
  24. Vieth R, Rao DS. Inaccuracies in relating 25-hydroxyvitamin D to ischemic heart disease. Eur J Epidemiol. 2003;18:461–462
  25. Hathcock J, Shao A, Vieth R, Heaney R. A risk assessment for vitamin D. Am J Clin Nutr. 2007;85:6–18
  26. Heaney RP, Dowell MS, Hale CA, Bendich A. Calcium absorption varies within the reference range for serum 25-hydroxyvitamin D. J Am Coll Nutr. 2003;22:142–146
  27. Heaney RP, Weaver CM. Calcium and vitamin D. Endocrinol Metab Clin North Am. 2003;32:181–194vii–viii
  28. Ursell MR, Vieth R, O'Connor PW, Gray B, Kimball S. A phase I dose-escalation study of vitamin D3 with calcium supplementation in patients with multiple sclerosis. Presented as a poster (P667) at the 21st Congress of the European Committee for the Treatment and Research in Multiple Sclerosis. September 28–October 1, 2005. Thessaloniki, Greece. Ref Type: Conference Proceeding
  29. Jacobus CH, Holick MF, Shao Q, Chen TC, Holm IA, Kolodny JM, et al. Hypervitaminosis D associated with drinking milk. N Engl J Med. 1992;326:1173–1177Comment in: N Engl J Med. 1992;326:1213–1215
  30. Vieth R. The mechanisms of vitamin D toxicity. Bone Miner. 1990;11:267–272
  31. ieth R, McCarten K, Norwich KH. Role of 25-hydroxyvitamin D3 dose in determining rat 1,25-dihydroxyvitamin D3 production. Am J Physiol. 1990;258:E780–E789
  32. Prosser DE, Jones G. Enzymes involved in the activation and inactivation of vitamin D. Trends Biochem Sci. 2004;29:664–673
  33. Selby PL, Davies M, Marks JS, Mawer EB. Vitamin D intoxication causes hypercalcaemia by increased bone resorption which responds to pamidronate. Clin Endocrinol (Oxf). 1995;43:531–536
  34. Suda T, Ueno Y, Fujii K, Shinki T. Vitamin D and bone. J Cell Biochem. 2003;88:259–266
  35. Jesudason D, Need AG, Horowitz M, O'Loughlin PD, Morris HA, Nordin BE. Relationship between serum 25-hydroxyvitamin D and bone resorption markers in vitamin D insufficiency. Bone. 2002;31:626–630
  36. Mawer EB, Backhouse J, Holman CA, Lumb GA, Stanbury SW. The distribution and storage of vitamin D and its metabolites in human tissues. Clin Sci. 1972;43:413–431
  37. HEALTH & CONSUMER PROTECTION DIRECTORATE-GENERAL. Opinion of the Scientific Committee on Food on the Tolerable Upper Intake Level of Vitamin D. EUROPEAN COMMISSION. Available at: http://europa.eu.int/comm/food/fs/sc/scf/out157_en.pdf. Accessed August 11, 2003. 2002. Brussels, Belgium. 1-10-0030. Ref Type: Report.

PII: S1047-2797(09)00039-8

doi: 10.1016/j.annepidem.2009.01.009

Annals of Epidemiology
Volume 19, Issue 7 , Pages 441-445 , July 2009

Article Tools

* Image Usage & Resolution