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Volume 19, Issue 11, Pages 808-814 (November 2009)


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Autism Spectrum Disorders in Preschool-Aged Children: Prevalence and Comparison to a School-Aged Population

Joyce S. Nicholas, PhDaCorresponding Author Informationemail address, Laura A. Carpenter, PhDb, Lydia B. King, MPHab, Walter Jenner, MSb, Jane M. Charles, MDb

Received 31 December 2008; accepted 27 April 2009. published online 22 June 2009.

Purpose

The purpose of this study was to determine the prevalence and case characteristics of children with autism spectrum disorders (ASDs) among 4-year-olds and to compare findings to previous prevalence estimates for 8-year-olds in the same geographic area.

Methods

South Carolina (SC) has been a participant in the Centers for Disease Control and Prevention's active, population-based, multiple-site ASD surveillance network for 8-year-olds since 2000. The 8-year-old methodology, designed to identify children both with and without prior diagnosis, was applied in SC with modification to include information sources for younger children.

Results

The ASD prevalence among 4-year-olds in 2006 was 8.0 per 1000 (95% confidence interval [CI], 6.1–9.9), or 1 in 125. In comparison, ASD prevalence among 8-year-olds in the same geographic area was 7.6 (95% CI, 5.7–9.5) in 2000 and 7.0 (95% CI 5.1–8.9) in 2002. Developmental concerns were documented at earlier ages across time, and while most cases received services, only 20% to 29% received services specific to ASD.

Conclusions

Findings should provide useful information for the planning of health/education policies and early intervention strategies for ASD.

a Department of Biostatistics, Bioinformatics, and Epidemiology, Medical University of South Carolina, Charleston, SC

b Department of Pediatrics, Division of Genetics and Developmental Pediatrics, Medical University of South Carolina, Charleston, SC

Corresponding Author InformationAddress correspondence to: Joyce S. Nicholas, PhD, Medical University of South Carolina, Department of Biostatistics, Bioinformatics, and Epidemiology, Department of Neurosciences, 135 Cannon St., Suite 303, MSC 835, Charleston, SC 29425-8350. Tel: (843) 876-1132. Fax: (843) 876-1126.

PII: S1047-2797(09)00125-2

doi:10.1016/j.annepidem.2009.04.005


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