Annals of Epidemiology
Volume 19, Issue 9 , Pages 630-636, September 2009

Employment Status, Coronary Heart Disease, and Stroke Among Women

  • April P. Carson, PhD

      Affiliations

    • Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC
    • Corresponding Author InformationAddress correspondence to: April P. Carson, PhD, Department of Epidemiology, University of Alabama at Birmingham, 220 RPHB, 1530 3rd Avenue S, Birmingham, AL 35294. Tel.: 205-934-6107; Fax: 205-934-8665.
  • ,
  • Kathryn M. Rose, PhD

      Affiliations

    • Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC
  • ,
  • Diane J. Catellier, DRPH

      Affiliations

    • Collaborative Studies Coordinating Center & Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC
  • ,
  • Ana V. Diez-Roux, MD, PhD

      Affiliations

    • Department of Epidemiology, University of Michigan, Ann Arbor, MI
  • ,
  • Carles Muntaner, MD, PhD

      Affiliations

    • Faculty of Nursing and Department of Public Health Sciences, University of Toronto, Toronto, Canada
  • ,
  • Sharon B. Wyatt, PhD

      Affiliations

    • School of Nursing and School of Medicine, University of Mississippi Medical Center, Jackson, MS

Received 6 December 2008; accepted 27 April 2009. published online 14 July 2009.

Purpose

To investigate the association of employment status with coronary heart disease (CHD) and ischemic stroke among middle-aged women.

Methods

Proportional hazards regression was used to assess the association of employment status, incident CHD, and incident ischemic stroke among 7,058 women, ages 45–64 years at baseline (1987–1989), from the Atherosclerosis Risk in Communities Study.

Results

After adjusting for age and race-field center, women employed outside the home had a decreased risk of CHD (hazard ratio [HR], 0.70; 95% confidence interval [95% CI], 0.56–0.86) and ischemic stroke (HR, 0.62; 95% CI, 0.47–0.84) compared with homemakers. Differences in cardiovascular disease risk factors partially accounted for the association of employment status and CHD (HR, 0.79; 95% CI, 0.63–0.99) and stroke (HR, 0.79; 95% CI, 0.58–1.08). Also, modest differences were noted when the results were stratified by education, with employed women having a lower risk of CHD (HR, 0.65; 95% CI, 0.45–0.93) than homemakers among those with less than a high school education.

Conclusions

Women employed outside of the home had a lower risk of CHD and stroke compared with homemakers and, for CHD, this association was stronger among women with less than a high school education. These findings suggest additional research into the varied occupational experiences of women, socioeconomic status, and health is warranted.

Key Words: Coronary Disease, Employment, Socioeconomic Status, Stroke, Women

Selected Abbreviations and Acronyms: HDL, high-density lipoprotein, CHD, coronary heart disease, ARIC, Atherosclerosis Risk in Communities Study, MI, myocardial infarction, LDL, low-density lipoprotein, CVD, cardiovascular disease, HR, hazard ratio, CI, confidence interval

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 The Atherosclerosis Risk in Communities Study is carried out as a collaborative study supported by National Heart, Lung, and Blood Institute contracts N01-HC-55015, N01-HC-55016, N01-HC-55018, N01-HC-55019, N01-HC-55020, N01-HC-55021, and N01-HC-55022.

PII: S1047-2797(09)00145-8

doi:10.1016/j.annepidem.2009.04.008

Annals of Epidemiology
Volume 19, Issue 9 , Pages 630-636, September 2009