Annals of Epidemiology
Volume 20, Issue 1 , Pages 82-85 , January 2010

Serum Calcium and Breast Cancer Risk in a Prospective Cohort Study

  • Brian L. Sprague, PhD

      Affiliations

    • Department of Population Health Sciences and Paul P. Carbone Comprehensive Cancer Center, University of Wisconsin, Madison, WI
    • Corresponding Author InformationAddress correspondence to: Brian Sprague, 610 Walnut St., WARF Room 307, Madison, WI 53726. Tel.: 608-263-0815; Fax: 608-265-5330.
    • ,
  • Halcyon G. Skinner, PhD

      Affiliations

    • Department of Population Health Sciences and Paul P. Carbone Comprehensive Cancer Center, University of Wisconsin, Madison, WI
    • ,
  • Amy Trentham-Dietz, PhD

      Affiliations

    • Department of Population Health Sciences and Paul P. Carbone Comprehensive Cancer Center, University of Wisconsin, Madison, WI
    • ,
  • Kristine E. Lee, MS

      Affiliations

    • Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI
    • ,
  • Barbara E.K. Klein, MD

      Affiliations

    • Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI
    • ,
  • Ronald Klein, MD

      Affiliations

    • Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI

References 

  1. Jacobson EA, James KA, Newmark HL, Carroll KK. Effects of dietary fat, calcium, and vitamin D on growth and mammary tumorigenesis induced by 7,12-dimethylbenz(a)anthracene in female Sprague-Dawley rats. Cancer Res. 1989;49:6300–6303
  2. Abou-Issa H, Moeschberger M, el-Masry W, Tejwani S, Curley RW, Webb TE. Relative efficacy of glucarate on the initiation and promotion phases of rat mammary carcinogenesis. Anticancer Res. 1995;15:805–810
  3. Kesse-Guyot E, Bertrais S, Duperray B, Arnault N, Bar-Hen A, Galan P, et al. Dairy products, calcium and the risk of breast cancer: Results of the French SUVIMAX prospective study. Ann Nutr Metab. 2007;51:139–145
  4. Lin J, Manson JE, Lee IM, Cook NR, Buring JE, Zhang SM. Intakes of calcium and vitamin D and breast cancer risk in women. Arch Intern Med. 2007;167:1050–1059
  5. Shin MH, Holmes MD, Hankinson SE, Wu K, Colditz GA, Willett WC. Intake of dairy products, calcium, and vitamin D and risk of breast cancer. J Natl Cancer Inst. 2002;94:1301–1311
  6. Giovannucci E. The epidemiology of vitamin D and cancer incidence and mortality: A review (United States). Cancer Causes Control. 2005;16:83–95
  7. McCarty MF. Parathyroid hormone may be a cancer promoter—an explanation for the decrease in cancer risk associated with ultraviolet light, calcium, and vitamin D. Med Hypotheses. 2000;54:475–482
  8. Almquist M, Manjer J, Bondeson L, Bondeson AG. Serum calcium and breast cancer risk: results from a prospective cohort study of 7,847 women. Cancer Causes Control. 2007;18:595–602
  9. Klein R, Klein BE, Linton KL, De Mets DL. The Beaver Dam Eye Study: Visual acuity. Ophthalmology. 1991;98:1310–1315
  10. Klein R, Klein BE, Lee KE. Changes in visual acuity in a population. The Beaver Dam Eye Study. Ophthalmology. 1996;103:1169–1178
  11. Watson JB, Lee K, Klein R, Klein BE, Koch DD. Epidemiological evidence for the disruption of ionized calcium homeostasis in the elderly. J Clin Epidemiol. 1997;50:845–849
  12. Gallagher SK, Johnson LK, Milne DB. Short-term and long-term variability of indices related to nutritional status. I: Ca, Cu, Fe, Mg, and Zn. Clin Chem. 1989;35:369–373
  13. Nordin BE, WIshart JM, Clifton PM, McArthur R, Scopacasa F, Need AG, et al. A longitudinal study of bone-related biochemical changes at the menopause. Clin Endocrinol (Oxf). 2004;61:123–130
  14. Moe SM. Disorders involving calcium, phosphorus, and magnesium. Prim Care. 2008;35:215–237v–vi

 This study was supported in part by faculty startup funds from the University of Wisconsin School of Medicine & Public Health, National Institutes of Health grants U10 EY006594 and R01 AG11099, and grant POP0504237 by the Komen for the Cure Breast Cancer Foundation.

PII: S1047-2797(09)00305-6

doi: 10.1016/j.annepidem.2009.09.001

Annals of Epidemiology
Volume 20, Issue 1 , Pages 82-85 , January 2010

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