Risk Factors and Impacts of Incident Tinnitus in Older Adults

Gopinath, Bamini; McMahon, Catherine M.; Rochtchina, Elena; Karpa, Michael J.; Mitchell, Paul

doi:10.1016/j.annepidem.2009.09.002

« Previous Next »Annals of Epidemiology
Volume 20, Issue 2 , Pages 129-135, February 2010

Risk Factors and Impacts of Incident Tinnitus in Older Adults

Bamini Gopinath, PhD
- Centre for Vision Research, Department of Ophthalmology, Westmead Millennium Institute, University of Sydney, Sydney, Australia
- Menzies Centre for Health Policy, University of Sydney, Sydney, Australia
Catherine M. McMahon, PhD
- Centre for Language Sciences, Linguistics Department, Macquarie University, Sydney, Australia
Elena Rochtchina, MApplStat
- Centre for Vision Research, Department of Ophthalmology, Westmead Millennium Institute, University of Sydney, Sydney, Australia
Michael J. Karpa, MBBS
- Centre for Vision Research, Department of Ophthalmology, Westmead Millennium Institute, University of Sydney, Sydney, Australia
Paul Mitchell, MD, PhD
- Centre for Vision Research, Department of Ophthalmology, Westmead Millennium Institute, University of Sydney, Sydney, Australia
- Address correspondence to: Professor Paul Mitchell, Centre for Vision Research, Department of Ophthalmology, University of Sydney, Westmead Hospital, Hawkesbury Road, Westmead, NSW, Australia, 2145. Tel.: 61 2 9845 7960; Fax: 61 2 9845 8345.

Received 22 June 2009; accepted 5 September 2009.

Purpose

We used a representative older population-based cohort to establish the predictors and impacts of tinnitus.

Methods

A total of 1,214 participants of the Blue Mountains Hearing Study were followed for 5 years (1997−1999 to 2002−2004). The presence of tinnitus was assessed by an audiologist-administered questionnaire. Hearing impairment was defined as the pure tone average (PTA)_0.5–4KHz>25 dB HL, in the better ear. Quality of life was measured by use of the Short Form 36-item Health Survey (SF-36). Depression was assessed using either the SF-36 (Mental Health Index, subscale) and the Center for Epidemiologic Studies Depression Scale.

Results

Symptomatic dizziness and hearing loss were significant risk factors for incident tinnitus, multivariable-adjusted odds ratio, 2.41 (95% confidence interval, 1.62–3.58) and odds ratio 2.31 (95% confidence interval, 1.46–3.66), respectively. Incident tinnitus cases demonstrated significantly lower mean SF-36 scores compared with subjects without tinnitus and were more likely to be depressed as assessed by both the Mental Health Index and Center for Epidemiologic Studies Depression Scale.

Conclusions

Incident tinnitus was predicted by two otological risk factors, dizziness and hearing loss. Temporal data documented diminished quality of life and psychological well-being in those subjects experiencing tinnitus. This finding highlights the importance of effective intervention strategies to prevent potentially debilitating morbidity associated with tinnitus.

Key words: Blue Mountains Eye Study, Blue Mountains Hearing Study, Depressive Symptoms, Dizziness, Hearing Loss, Neck Injury, Quality of Life, Tinnitus

Selected Abbreviations and Acronyms: EHLS, Epidemiology of Hearing Loss Study, SF-36, 36-Item-Short-Form Health Survey, BMHS, The Blue Mountains Hearing Study, BMES, Blue Mountains Eye Study, PTA, pure-tone average, MHI, Mental Health Index, CES-D-10, Center for Epidemiologic Studies Short Depression Scale, OR, odds ratio, CI, confidence interval, PAR, population-attributable risk

To access this article, please choose from the options below

The Blue Mountains Eye Study was supported by the Australian National Health and Medical Research Council (Grants 974159, 991407, 211069, and 262120).

PII: S1047-2797(09)00306-8

doi:10.1016/j.annepidem.2009.09.002

« Previous Next »Annals of Epidemiology
Volume 20, Issue 2 , Pages 129-135, February 2010

Access this article on SciVerse ScienceDirect